PAD4-IN-2, CAS 2642327-52-2

Product Description: PAD4-IN-2 (compound 5i) is a PAD4 inhibitor (IC50=1.94 μM). PAD4-IN-2 inhibits tumor growth in mice by specifically inhibiting the PAD4-H3cit-NETs pathway in neutrophils[1].

Applications: Cancer-programmed cell death

Formula: C20H23BClN7O6

References: [1]Zhu D, et al. Highly-tumor-targeted PAD4 inhibitors with PBA modification inhibit tumors in vivo by specifically inhibiting the PAD4-H3cit-NETs pathway in neutrophils. Eur J Med Chem. 2023 Oct 5;258:115619.

CAS Number: 2642327-52-2

Molecular Weight: 503.70

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Protein Arginine Deiminase

• SKU: MEXHY-155052-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-155052-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK