PAD4-IN-2 (TFA)

Product Description: PAD4-IN-2 (compound 5i) TFA is a PAD4 inhibitor (IC50=1.94 μM). PAD4-IN-2 TFA inhibits tumor growth in mice by specifically inhibiting the PAD4-H3cit-NETs pathway in neutrophils[1].

Formula: C22H24BClF3N7O8

References: [1]Zhu D, et al. Highly-tumor-targeted PAD4 inhibitors with PBA modification inhibit tumors in vivo by specifically inhibiting the PAD4-H3cit-NETs pathway in neutrophils. Eur J Med Chem. 2023 Oct 5;258:115619.

Molecular Weight: 617.73

Compound Purity: 95.64

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Protein Arginine Deiminase

• SKU: MEXHY-155052A-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-155052A-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK