PARP7-IN-16, CAS 2435657-10-4

Product Description: PARP7-IN-16 (compound 36) is a potent, selective and orally active inhibitor of PARP-1/2/7, with IC50s of 0.94, 0.87 and 0.21 nM, respectively. PARP7-IN-16 can be used for the research of breast cancer and prostate cancer[1].

Formula: C25H26FN4NaO4

References: [1]Zhou J, et, al. Discovery of Quinazoline-2,4(1 H,3 H)-dione Derivatives Containing a Piperizinone Moiety as Potent PARP-1/2 Inhibitors─Design, Synthesis, In Vivo Antitumor Activity, and X-ray Crystal Structure Analysis. J Med Chem. 2023 Oct 26;66(20):14095-14115.

CAS Number: 2435657-10-4

Molecular Weight: 488.49

Compound Purity: 99.91

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: PARP

• SKU: MEXHY-156419-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-156419-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK