PD-1/PD-L1-IN-43

Product Description: PD-1/PD-L1-IN-43 (compound Z13) is a small-molecule inhibitors targeting the PD-1/PD-L1 interaction. PD-1/PD-L1-IN-43 exhibites potent in vivo antitumor efficacy against B16-F10 melanoma. PD-1/PD-L1-IN-43 inhibits tumor growth by blocking the interaction between PD-1 and PD-L1. PD-1/PD-L1-IN-43 can be used in anti-tumor studies[1].

Formula: C27H25N3O4

References: [1]Xu C, et al. Discovery of 4-phenyl-1H-indazole derivatives as novel small-molecule inhibitors targeting the PD-1/PD-L1 interaction[J]. Bioorganic Chemistry, 2024: 107376.

Molecular Weight: 455.51

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PD-1/PD-L1

• SKU: MEXHY-163534-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163534-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK