PD-1/PD-L1-IN-44

Product Description: PD-1/PD-L1-IN-44 (Compound 22) selectively inhibits PD-1/PD-L1 proteins (IC50=1.21 nM). PD-1/PD-L1-IN-44 inhibits tumor growth without toxicity in animal models and increases CD8+ cell infiltration[1].

Formula: C34H30N2O6

References: [1]Zhang Y, et al. Improving tumor sensitivity by the introduction of an ester chain to triaryl derivatives targeting PD-1/PD-L1. Eur J Med Chem. 2024 May 5;271:116433.

Molecular Weight: 562.61

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PD-1/PD-L1

• SKU: MEXHY-161518-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161518-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK