Product Description: PDDHV is a calcium absorption inducer and may achieve 45Ca2+ influx by stimulating vanillic acid receptor VR1. PDDHV induces 45Ca2+ uptake (EC50: 70 nM) in rat dorsal root ganglion neurons (expressing native vanilloid receptors) and calcium mobilization (EC50: 125 nM) in VR1-transfected CHO cells. PDDHV also inhibits [3H]-resiniferatoxin (RTX) binding to the dorsal root ganglion membrane in rats[1].
Formula: C49H72O11
References: [1]Szallasi A, Szabo T, Biro T, et al. Resiniferatoxin‐type phorboid vanilloids display capsaicin‐like selectivity at native vanilloid receptors on rat DRG neurons and at the cloned vanilloid receptor VR1[J]. British journal of pharmacology, 1999, 128(2): 428-434.
CAS Number: 179469-40-0
Molecular Weight: 837.09
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Calcium Channel
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