PDE4-IN-15

Product Description: PDE4-IN-15 (compound 7b-1) is an inhibitor of PDE4 (IC50 = 0.17 μM) and has anti-TNF-α activity (EC50 = 0.19 μM). PDE4-IN-15 has a good skin permeability[1].

Formula: C23H30O6

References: [1]Chenming Gu, et al. Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model. J Med Chem. 2024, 67, 6.

Molecular Weight: 402.48

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Phosphodiesterase (PDE);TNF Receptor

• SKU: MEXHY-161381-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161381-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK