PDK1-IN-2, CAS 1643958-85-3

Product Description: PDK1-IN-2 is a small molecule inhibitor of 3-phosphoinositol-dependent protein kinase-1 (PDK1). PDK1-IN-2 inhibits the binding of PDK1 to its substrate by competitively binding to the PIF pocket of PDK1, thereby inhibiting the kinase activity and downstream signaling of PDK1. PDK1-IN-2 can be used for cell survival and proliferation in cancer[1].

Formula: C15H9ClN2O2S3

References: [1]Rettenmaier T J, et al. A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1[J]. Proceedings of the National Academy of Sciences, 2014, 111(52): 18590-18595.

CAS Number: 1643958-85-3

Molecular Weight: 380.89

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PDK-1

• SKU: MEXHY-117809-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-117809-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK