Penpaxilloids A

Product Description: Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A are also α-glucosidase (α-glucosidase) inhibitors and have anti-inflammatory activity[1].

Formula: C31H37NO7

References: [1]Dai LT, et al. Anti-diabetic and anti-inflammatory indole diterpenes from the marine-derived fungus Penicillium sp. ZYX-Z-143. Bioorg Chem. 2024 Apr;145:107205.

Molecular Weight: 535.63

Research Area: Metabolic Disease; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Glucosidase;Phosphatase

• SKU: MEXHY-N12761-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N12761-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK