PERK/eIF2α activator 1, CAS 1178583-17-9

PERK/eIF2α activator 1, CAS 1178583-17-9
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MEXHY-158196-0
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MedChemExpress

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Product Description: PERK/eIF2α activator 1 (compound V8) is a flavonoid with an anti-tumor activity. PERK/eIF2α activator 1 induces apoptosis and activates the PERK-eIF2α-ATF4 pathway. PERK/eIF2α activator 1 inhibits HepG2 cell proliferation with an IC50 value of 23 μM[1].

Formula: C24H29NO7

References: [1]Yi Zhang, et al. V8, a newly synthetic flavonoid, induces apoptosis through ROS-mediated ER stress pathway in hepatocellular carcinoma. Arch Toxicol. 2014, 88, 1.

CAS Number: 1178583-17-9

Molecular Weight: 443.49

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;PERK
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SKU MEXHY-158196-0
Manufacturer MedChemExpress
Manufacturer SKU HY-158196-0
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