PI3K/Akt/mTOR-IN-4

Product Description: PI3K/Akt/mTOR-IN-4 (compound 4r) is a potent PI3K/Akt/mTOR and tubulin polymerization inhibitor. PI3K/Akt/mTOR-IN-4 induce apoptosis and cell cycle arrest at G2/M phase. PI3K/Akt/mTOR-IN-4 decreases the expression of p-PI3K, p-Akt, and p-mTOR, β-tubulin[1].

Formula: C29H29FN4O3

References: [1]Li SS, et al. Design, synthesis, and biological evaluation of novel benzimidazole derivatives as anti-cervical cancer agents through PI3K/Akt/mTOR pathway and tubulin inhibition. Eur J Med Chem. 2024 Apr 16;271:116425.

Molecular Weight: 500.56

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Akt;Apoptosis;Microtubule/Tubulin;mTOR;PI3K

• SKU: MEXHY-163511-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163511-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK