PI3Kδ-IN-15, CAS 870281-17-7

Product Description: PI3Kδ-IN-15 (compound 6b) is a selective PI3Kδ inhibitor with an IC50 of 0.5 nM for p110δ. PI3Kδ-IN-15 inhibits PI3Kδ with >30-fold higher potency than PI3Kγ, PI3Kβ, and PI3Kα[1].

Formula: C21H16FN7O

References: [1]Yeon Su Kim, et al. Synthesis and biological evaluation of novel purinyl quinazolinone derivatives as PI3Kδ-specific inhibitors for the treatment of hematologic malignancies. Bioorg Med Chem. 2021 Sep 1;45:116312.

CAS Number: 870281-17-7

Molecular Weight: 401.40

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PI3K

• SKU: MEXHY-108418-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108418-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK