PI3Kδ-IN-20

Product Description: PI3Kδ-IN-20 (compound ( S )-36) is a potent inhibitor of PI3Kδ, with the IC50 of 6.4 nM. PI3Kδ-IN-20 has oral bioactivity. PI3Kδ-IN-20 shows significant suppression of cell proliferation and remarkable induction of apoptosis both in vitro and in vivo[1].

Formula: C20H17ClN8

References: [1]Yongmei Tang, et al. Discovery of Potent and Selective PI3Kδ Inhibitors for the Treatment of Acute Myeloid Leukemia. J Med Chem. 2024 Apr 25;67(8):6638-6657.

Molecular Weight: 404.86

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: PI3K

• SKU: MEXHY-158147-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-158147-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK