PIKfyve-IN-3

Product Description: PIKfyve-IN-3 (compound L22) has a remarkable interaction with PIKfyve kinase with a Kd value of 0.47 nM. PIKfyve-IN-3 has oral activity. PIKfyve-IN-3 inhibits tumor growth in a HeLa xenograft model[1].

Formula: C21H23N5O

References: [1]Yong Chen, et al. Discovery of Potent and Selective Phosphatidylinositol 3-Phosphate 5-Kinase (PIKfyve) Inhibitors as Methuosis Inducers. J Med Chem. 2024, 67, 1.

Molecular Weight: 361.44

Compound Purity: 99.55

Research Area: Cancer

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: PIKfyve

• SKU: MEXHY-163133-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163133-10.1
• Green Labware: No
• Package Unit: 10mM/1mL
• Quantity Unit: STK