Product Description: PIM3-IN-1 hydrochloride (Compound 19a) is an inhibitor of (PIM2/3), with the highest inhibition level being against PIM3, having an IC50 value in the nanomolar range. PIM3-IN-1 hydrochloride can be used in cancer research[1].
Formula: C23H23Cl2N5
References: [1]Frazier T, et al. Synthesis, kinase inhibition and anti-leukemic activities of diversely substituted indolopyrazolocarbazoles. Eur J Med Chem. 2024;269:116352.
Molecular Weight: 440.37
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Pim