Pipernonaline, CAS 88660-10-0

Product Description: Pipernonaline is a piperine derivative with antiprostate cancer activity. Pipernonaline inhibits the proliferation of androgen-dependent/independent LNCaP/PC-3 prostate cells. Pipernonaline activates caspase-3 and promotes procaspase-3/PARP cleavage. Pipernonaline also mediates reactive oxygen species (ROS) production, increased intracellular Ca(2+), and mitochondrial membrane depolarization[1].

Applications: Cancer-programmed cell death

Formula: C21H27NO3

References: [1]Lee W, et al. Pipernonaline from Piper longum Linn. induces ROS-mediated apoptosis in human prostate cancer PC-3 cells. Biochem Biophys Res Commun. 2013 Jan 4;430(1):406-12..

CAS Number: 88660-10-0

Molecular Weight: 341.44

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Caspase

• SKU: MEXHY-W748509-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W748509-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK