Pirfenidone, CAS 53179-13-8

Description: Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tumor cell proliferation. This agent also inhibits DNA synthesis and the production of mRNA for collagen types I and III, resulting in a reduction in radiation-induced fibrosis.

CAS Number: 53179-13-8

Formula: C12H11NO

Molecular Weight: 185,22

References: Nakazato H, et al. Eur J Pharmacol, 2002, 446(1-3), 177-185.

• SKU: TGMT2386-1g
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T2386-1g
• Package Unit: 1 g
• Quantity Unit: STK