Pirmitegravir, CAS 2245231-10-9

Product Description: Pirmitegravir is a potent and first-in-class inhibitor of allosteric integrase (ALLINI) that targets LEDGF/p75 binding site. Pirmitegravir displays picomolar IC50 in human PBMCs with a >24,000 therapeutic index against HIV-1. Pirmitegravir harbors outstanding anti-virus and safety properties[1].

Applications: COVID-19-anti-virus

Formula: C27H31ClN4O3

References: [1]Maehigashi T, et al. A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site. PLoS Pathog. 2021;17(7):e1009671.

CAS Number: 2245231-10-9

Molecular Weight: 495.01

Research Area: Infection

Solubility: 10 mM in DMSO

Target: HIV;HIV Integrase

• SKU: MEXHY-130000-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-130000-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK