PKM2-IN-3, CAS 2408841-19-8

Product Description: PKM2-IN-3 is an inhibitor of PKM2 kinase with an IC50 value of 4.1 μM. PKM2-IN-3 exhibits an anti-neuroinflammatory effect by inhibiting PKM2-mediated glycolysis and NLRP3 activation[1].

Applications: Neuroscience-Neuromodulation

Formula: C21H22O4

References: [1]Gao CL, et al. Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti-Neuroinflammatory Agents for Ischemic Stroke. Angew Chem Int Ed Engl. 2020;59(6):2429-2439.

CAS Number: 2408841-19-8

Molecular Weight: 338.40

Compound Purity: 99.44

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Pyruvate Kinase

• SKU: MEXHY-139667-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-139667-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK