Plasma kallikrein-IN-5

Product Description: Plasma kallikrein-IN-5 (Compound 20) is a potent covalent inhibitor of plasma potassium kinin peptide (Pka) with IC50 values of 66 nM and 70 pM at 1 minute and 24 hours, respectively. Plasma kallikrein-IN-5 can be used IN the study of hereditary angioedema (HAE)[1].

Applications: Neuroscience-Neuromodulation

Formula: C29H33BFN5O3

References: [1]Allison M, et al. Discovery of α-Amidobenzylboronates as Highly Potent Covalent Inhibitors of Plasma Kallikrein. ACS Med Chem Lett. 2024 Mar 28;15(4):501-509.

Molecular Weight: 529.41

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Kallikrein

• SKU: MEXHY-163464-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163464-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK