Plitidepsin (Standard), CAS 137219-37-5

Product Description: Plitidepsin (Standard) is the analytical standard of Plitidepsin. This product is intended for research and analytical applications. Plitidepsin (Aplidine) is a potent anti-cancer agent by targeting eEF1A2 ( KD=80 nM)[1]. Plitidepsin possesses antiviral activity and is against SARS-CoV-2 with an IC90 of 0.88 nM. Plitidepsin is usually used for multiple myeloma and advanced cancer research, and has the potential for COVID-19 research[1][2].

Formula: N/A

References: [1]Alejandro Losada, et al. Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin. Sci Rep. 2016 Oct 7;6:35100./[2]Kris M White, et al. Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A. Science. 2021 Feb 26;371(6532):926-931.

CAS Number: 137219-37-5

Molecular Weight: N/A

Research Area: Cancer; Infection

Target: DNA/RNA Synthesis;SARS-CoV

• SKU: MEXHY-16050R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-16050R-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK