PLK1/BRD4-IN-3, CAS 2251709-91-6

Product Description: PLK1/BRD4-IN-3 (Compound 21) is a selective dual inhibitor for bromodomain 4 (BRD4) and polo-like kinase 1 (PLK1). PLK1/BRD4-IN-3 inhibits BRD4-BD1, PLK1 and BRDT-BD1, with IC50s of 0.059, 0.127 and 0.245 μM, respectively[1].

Formula: C31H43N7O3

References: [1]Liu S, et al., Structure-Guided Design and Development of Potent and Selective Dual Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors. J Med Chem. 2018 Sep 13;61(17):7785-7795.

CAS Number: 2251709-91-6

Molecular Weight: 561.72

Compound Purity: 99.66

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Epigenetic Reader Domain;Polo-like Kinase (PLK)

• SKU: MEXHY-160558-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-160558-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK