Product Description: Pneumolysin-IN-1 (compound PB-3) is a targeted small molecule inhibitor of Pneumolysin (PLY) (IC50=3.1 µM). Pneumolysin-IN-1 is a pore blocking agent and an anti-virulence factor. Pneumolysin-IN-1 can be used to study the infection caused by Streptococcus pneumoniae[1].
Formula: C23H16Cl2N2O4
References: [1]Aziz U B A, et al. Targeted small molecule inhibitors blocking the cytolytic effects of pneumolysin and homologous toxins[J]. Nature Communications, 2024, 15(1): 3537.