Product Description: Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cys (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant 1,4-dimercaptothreitol (DTT) and the inhibitor N-ethylmaleimide (NEM) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism[1].
Formula: C33H31NO7S
References: [1]Jia D, et al. Near-Infrared Fluorescence Probe with a New Recognition Moiety for the Specific Detection of Cysteine to Study the Corresponding Physiological Processes in Cells, Zebrafish, and <i>Arabidopsis thaliana</i>. Anal Chem. 2024;96(15):6030-6036.
Molecular Weight: 585.67
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Fluorescent Dye