Product Description: PTP1B-IN-26 (Compound 7a) is a derivative of phenylthiosemicarbazide‐phenoxy‐1,2,3‐triazole‐N‐phenylacetamide. PTP1B-IN-26 is an inhibitor of protein tyrosine phosphatase 1B (PTP-1B). PTP1B-IN-26 is a competitive inhibitor. PTP1B-IN-26 can be used to research in type 2 diabetes.
Formula: C25H23N7O2S
References: [1]Ansariashlaghi S, Fakhrioliaei A, Mohammadi‐Khanaposhtani M, et al. New phenylthiosemicarbazide‐phenoxy‐1, 2, 3‐triazole‐N‐phenylacetamides as dual inhibitors against α‐glucosidase and PTP‐1B for the treatment of type 2 diabetes[J]. Archiv der Pharmazie, 2024: e2300517.
Molecular Weight: 485.56
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Amyloid-β;Phosphatase