PTP1B-IN-27

Product Description: PTP1B-IN-27 (Compound 7i) is an inhibitor of protein tyrosine phosphatase 1-B (PTP‐1B)(IC50=8.2 µM). PTP1B-IN-27 also inhibits α-Glucosidase (IC50=120 µM) and shows competitive inhibition (Ki=118 µM)[1].

Formula: C26H24FN7O2S

References: [1]Ansariashlaghi S, et al. New phenylthiosemicarbazide-phenoxy-1,2,3-triazole-N-phenylacetamides as dual inhibitors against α-glucosidase and PTP-1B for the treatment of type 2 diabetes. Arch Pharm (Weinheim). 2024 Apr 9:e2300517.

Molecular Weight: 517.58

Research Area: Endocrinology

Solubility: 10 mM in DMSO

Target: Glucosidase;Phosphatase

• SKU: MEXHY-162480-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162480-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK