PYRIB-SO 2

Product Description: PYRIB-SO 2 is a potent antimitotic agent. PYRIB-SO 2 shows antiproliferative activity and induces cell cycle arrest at G2/M phase. PYRIB-SO 2 reduces and disruptes microtubule structures. PYRIB-SO 2 binds to the colchicine-binding site (C-BS) of α, β-tubulin[1].

Formula: C14H12ClN3O4S

References: [1]Ouellette V, et al. Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site. Bioorg Med Chem Lett. 2024 Jun 1;105:129745.

Molecular Weight: 353.78

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Microtubule/Tubulin

• SKU: MEXHY-163523-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163523-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK