Product Description: (R)-3,4-DCPG is an AMPA and NMDA antagonist with a Kd of 77 μM for AMPA. (R)-3,4-DCPG complete antagonizes the NMDA-induced depolarization at a concentration of 500 μM. (R)-3,4-DCPG exhibits a weak antagonistic effect on kainate-induced depolarizations[1].
Formula: C10H9NO6
References: [1]N K Thomas, et al. Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur J Pharmacol. 1997 Nov 5;338(2):111-6.
CAS Number: 201730-10-1
Molecular Weight: 239.18
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: iGluR