Product Description: Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9[1][2].
Applications: Cancer-programmed cell death
Formula: C28H18O2
References: [1]Yanheng Chen, et al. <i>H. pylori</i> infection confers resistance to apoptosis via Brd4-dependent <i>BIRC3</i> eRNA synthesis. Cell Death Dis. 2020 Aug 21;11(8):667./[2]Rahul Palchaudhuri,et al. A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed. Cell Rep. 2015 Dec 1;13(9):2027-36.
CAS Number: 1176-09-6
Molecular Weight: 386.44
Compound Purity: 98.0
Research Area: Cancer
Solubility: DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Apoptosis;Caspase
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