Resatorvid, CAS 243984-11-4

Description: Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid binds directly to Cys747 and prevents TLR4 from binding to TIRAP, thereby blocking downstream signaling. Resatorvid has antitumor activity, anti-inflammatory activity, and neuroprotective effects.

CAS Number: 243984-11-4

Formula: C15H17ClFNO4S

Molecular Weight: 361,82

References: Zandi Z, et al. The anticancer effect of the TLR4 inhibition using TAK-242 (resatorvid) either as a single agent or in combination with chemotherapy: A novel therapeutic potential for breast cancer. J Cell Biochem. 2020 Feb;121(2):1623-1634.

• SKU: TGMTQ0181-50mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: TQ0181-50mg
• Package Unit: 50 mg
• Quantity Unit: STK