Ribociclib (Standard), CAS 1211441-98-3

Product Description: Ribociclib (Standard) is the analytical standard of Ribociclib. This product is intended for research and analytical applications. Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1].

Formula: N/A

References: [1]VanArsdale T, et al. Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment. Clin Cancer Res. 2015 Jul 1;21(13):2905-10./[2]Rader J, et al. Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma. Clin Cancer Res. 2013 Nov 15;19(22):6173-82.

CAS Number: 1211441-98-3

Molecular Weight: N/A

Research Area: Cancer

Target: CDK

• SKU: MEXHY-15777R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15777R-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK