Product Description: Rp-8-pCPT-cGMPS sodium is the sodium salt form of Rp-8-pCPT-cGMPS. Rp-8-pCPT-cGMPS is an inhibitor for cGMP-dependent protein kinase (cGK). Rp-8-pCPT-cGMPS sodium is an agonist for cyclic nucleotide-gated (CNG) channels in a voltage-dependent manner[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C16H14ClN5NaO6PS2
References: [1]Liu S, et al., cGMP and cGMP-dependent protein kinase I pathway in dorsal root ganglia contributes to bone cancer pain in rats. Spine (Phila Pa 1976). 2014 Sep 1;39(19):1533-41./[2]Wei JY, et al., Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci. 1998 Feb;10(1):53-64.
CAS Number: 208445-07-2
Molecular Weight: 525.86
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: PKG