RSL3, CAS 1219810-16-8

Description: RSL3 (RSL3 1S) is an inhibitor of GPX4, and inhibits system xc- that blocks GSH synthesis (IC50=100 nM). RSL3 is a VDAC-independent activator of iron death that is selective for tumor cells carrying oncogenic RAS.

CAS Number: 1219810-16-8

Formula: C23H21ClN2O5

Molecular Weight: 440,88

References: Asperti M, et al. H-ferritin suppression and pronounced mitochondrial respiration make Hepatocellular Carcinoma cells sensitive to RSL3-induced ferroptosis. Free Radic Biol Med. 2021 Jun;169:294-303.

• SKU: TGMT3646-25mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T3646-25mg
• Package Unit: 25 mg
• Quantity Unit: STK