RU.521, CAS 2262452-06-0

Description: RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.

CAS Number: 2262452-06-0

Formula: C19H12Cl2N4O3

Molecular Weight: 415,23

References: Vincent J, et al. Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun. 2017 Sep 29;8(1):750.

• SKU: TGMT5486-10mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T5486-10mg
• Package Unit: 10 mg
• Quantity Unit: STK