Ruxolitinib, CAS 941678-49-5

Description: Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.

CAS Number: 941678-49-5

Formula: C17H18N6

Molecular Weight: 306,36

References: Quintás-Cardama A, et al. Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms. Blood. 2010 Apr 15;115(15):3109-17.

• SKU: TGMT1829-5mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T1829-5mg
• Package Unit: 5 mg
• Quantity Unit: STK