Product Description: Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a lipase inhibitor (IC50: 1 μM)[1][2][3].
Formula: C18H16O5
References: [1]William A. et al. Metabolites produced by the Scleroderris canker fungus, Gremmeniellaabietina. Part 1. Canadian Journal of Chemistry. 1986. 64(8): 1585-1589./[2]Hidayat Hussain, et al. Phytochemical investigation and antimicrobial activity of an endophytic fungus Phoma sp.Journal of King Saud University - Science. Volume 27, Issue 1, January 2015, Pages 92-95. /[3]Macabeo APG, et al. Alpha-Glucosidase- and Lipase-Inhibitory Phenalenones from a New Species of Pseudolophiostoma Originating from Thailand. Molecules. 2020 Feb 20;25(4):965.
CAS Number: 104855-19-8
Molecular Weight: 312.32
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Fungal;Lipase
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