Selinexor (Standard), CAS 1393477-72-9

Selinexor (Standard), CAS 1393477-72-9
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MEXHY-17536R-0
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MedChemExpress

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Product Description: Selinexor (Standard) is the analytical standard of Selinexor. This product is intended for research and analytical applications. Selinexor (KPT-330), analog of KPT-185, is an orally bioavailable and selective CRM1 inhibitor[1][2].

Formula: N/A

References: [1]Etchin J, et al. KPT-330 inhibitor of CRM1 (XPO1)-mediated nuclear export has selective anti-leukaemic activity in preclinical models of T-cell acute lymphoblastic leukaemia and acute myeloid leukaemia. Br J Haematol. 2013 Apr;161(1):117-27./[2]Tai YT, et al. CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications. Leukemia. 2014 Jan;28(1):155-65.

CAS Number: 1393477-72-9

Molecular Weight: N/A

Research Area: Cancer

Target: CRM1
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SKU MEXHY-17536R-0
Manufacturer MedChemExpress
Manufacturer SKU HY-17536R-0
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