Description: Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM). Selisistat can be used in the study of neurological disorders such as Huntington's chorea.
CAS Number: 49843-98-3
Formula: C13H13ClN2O
Molecular Weight: 248,71
References: Kabra N, et al. SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J Biol Chem. 2009 Jul 3;284(27):18210-7.