Setileuton, CAS 910656-27-8

Setileuton, CAS 910656-27-8
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MEXHY-10437-0
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MedChemExpress

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Product Description: Setileuton (MK-0633) is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC50 of 3.9 and 52 nM, respectively[1].

Formula: C22H17F4N3O4

References: [1]Ducharme Y, et al., The discovery of setileuton, a potent and selective 5-lipoxygenase inhibitor. ACS Med Chem Lett. 2010 Apr 13;1(4):170-4.

CAS Number: 910656-27-8

Molecular Weight: 463.38

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Lipoxygenase
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SKU MEXHY-10437-0
Manufacturer MedChemExpress
Manufacturer SKU HY-10437-0
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