Smad2/3-IN-2

Product Description: Smad2/3-IN-2 (Compound 3) is an inhibitor for TGF-β-dependent Smad2/3 and IL-4-dependent STAT6 signaling pathway, with IC50s of 90 and 20 nM, respectively[1].

Formula: C18H21ClO5

References: [1]Seipp K, et al., Total Synthesis, Structure Reassignment, and Biological Evaluation of the Anti-Inflammatory Macrolactone 13-Hydroxy-14-deoxyoxacyclododecindione. J Nat Prod. 2024 Mar 31.

Molecular Weight: 352.81

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: STAT;TGF-beta/Smad

• SKU: MEXHY-162404-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162404-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK