SMO-IN-2, CAS 1822355-27-0

Product Description: SMO-IN-2 (compound 1) is a potent smoothened (SMO) inhibitor with an IC50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].

Applications: Cancer-programmed cell death

Formula: C25H25F4N5O2

References: [1]Ji D, et al. Design, synthesis and biological evaluation of anthranilamide derivatives as potent SMO inhibitors. Bioorg Med Chem. 2020 Mar 15;28(6):115354.

CAS Number: 1822355-27-0

Molecular Weight: 503.49

Compound Purity: 98.12

Research Area: Cancer

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Hedgehog;Smo

• SKU: MEXHY-150564-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-150564-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK