Product Description: Sodium dichloroacetate is a metabolic regulator in cancer cells' mitochondria with anticancer activity. Sodium dichloroacetate inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. Sodium dichloroacetate increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. Sodium dichloroacetate also works as NKCC inhibitor[1].
Applications: Cancer-Kinase/protease
Formula: C2HCl2NaO2
References: [1]Stakišaitis D, et al. The Importance of Gender-Related Anticancer Research on Mitochondrial Regulator Sodium Dichloroacetate in Preclinical Studies In Vivo. Cancers (Basel). 2019 Aug 20;11(8). pii: E1210.
CAS Number: 2156-56-1
Molecular Weight: 150.92
Compound Purity: 99.76
Research Area: Cancer
Solubility: H2O : 100 mg/mL (ultrasonic)
Target: Apoptosis;NKCC;PDHK;Reactive Oxygen Species