SOS1 Ligand intermediate-5

Product Description: SOS1 Ligand intermediate-5 is the ligand for son of sevenless 1 (SOS1). SOS1 Ligand intermediate-5 is utilized for synthesis of PROTAC SOS1 degrader-10 (HY-161654)[1].

Formula: C24H26F3N5O3

References: [1]Wang, K, et al. “Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor.” Bioorganic & medicinal chemistry letters vol. 107 (2024): 129780.

Molecular Weight: 489.49

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Ligands for Target Protein for PROTAC

• SKU: MEXHY-161655-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161655-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK