Sotorasib, CAS 2296729-00-3

Description: Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib exhibits inhibitory activity against KRAS G12C mutant tumors.

CAS Number: 2296729-00-3

Formula: C30H30F2N6O3

Molecular Weight: 560,59

References: Canon J, et al. The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity. Nature. 2019 Nov;575(7781):217-223.

• SKU: TGMT8684-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T8684-1mL
• Package Unit: 1 mL
• Quantity Unit: STK