SP600125, CAS 129-56-6

Description: SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.

CAS Number: 129-56-6

Formula: C14H8N2O

Molecular Weight: 220,23

References: Li CH, et al. Enhancement of radiosensitivity by inhibition of c-Jun N-terminal kinase activity in a Lewis lung carcinoma‑bearing subcutaneous tumor mouse model. Oncol Rep. 2016 Dec;36(6):3397-3404.

• SKU: TGMT3109-10mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T3109-10mg
• Package Unit: 10 mg
• Quantity Unit: STK