SPDZi1

Product Description: SPDZi1 is a potent and selective syntenin inhibitor that binds to PDZ1 and PDZ2 domains of syntenin. SPDZi1 binds to the syntenin PDZ tandem (STNPDZ) with a Kd of 3.6 μM. SPDZi1 suppresses glioblastoma and reduces the activation of NF-κB, a downstream effector of syntenin[1].

Formula: C22H19N3O5

References: [1]Yunseok Heo, et al. Discovery of a potent inhibitor that suppresses glioblastoma by dual targeting of both syntenin PDZ domains. bioRxiv preprint. April 04, 2024.

Molecular Weight: 405.40

Research Area: Cancer

Target: NF-κB

• SKU: MEXHY-162510-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162510-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK