SPP-002

Product Description: SPP-002 is a sulfate analogue that acts as a potential Sialyltransferase (ST) inhibitor. SPP-002 selectively inhibits n-glycosialylation with inhibition at least an order of magnitude greater than that of unmodified parental cholic acid (LCA). SPP-002 reduces tumor cell migration and invasion by inhibiting the integrin /FAK/Paxillin signaling pathway. SPP-002 can be used in the study of tumor metastasis[1].

Formula: C24H41KO5S

References: [1]Perez S J L P, et al. Biological evaluation of sulfonate and sulfate analogues of lithocholic acid: A bioisosterism-guided approach towards the discovery of potential sialyltransferase inhibitors for antimetastatic study[J]. Bioorganic & Medicinal Chemistry Letters, 2024, 105: 129760.

Molecular Weight: 480.74

Research Area: Cancer

Target: Sialyltransferase

• SKU: MEXHY-163548-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163548-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK