SPSB2-iNOS inhibitory cyclic peptide-1 (TFA)

Product Description: SPSB2-iNOS inhibitory cyclic peptide-1 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-1(HY-P10383). SPSB2-iNOS inhibitory cyclic peptide-1 is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 4.4 nM. SPSB2-iNOS inhibitory cyclic peptide-1 is resistant to the proteases pepsin, trypsin and α-chymotrypsin. SPSB2-iNOS inhibitory cyclic peptide-1 is stable in human plasma and in oxidative environment[1].

Formula: C35H56N12O14S2.xC2HF3O2

References: [1]Yap BK, et al., A potent cyclic peptide targeting SPSB2 protein as a potential anti-infective agent. J Med Chem. 2014 Aug 28;57(16):7006-15.

Molecular Weight: 933.02 (free acid)

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-P10383A-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10383A-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK