Product Description: ssRNA40 (sodium) is a 20-mer phosphothioate protected single-stranded RNA oligonucleotide. ssRNA40 is a uridine-rich ssRNA derived from the HIV-1 long terminal repeat on activation of NK cells via TLR7/8[1][2].
Applications: COVID-19-immunoregulation
Formula: N/A
References: [1]Hiromi Tanji, et al. Toll-like receptor 8 senses degradation products of single-stranded RNA. Nat Struct Mol Biol. 2015, 22, 2./[2]Alter G, Suscovich TJ, Teigen N, et al. Single-stranded RNA derived from HIV-1 serves as a potent activator of NK cells. J Immunol. 2007;178(12):7658-7666.
Molecular Weight: N/A
Compound Purity: 93.25
Research Area: Infection
Solubility: 10 mM in DMSO/10 mM in H2O
Target: Toll-like Receptor (TLR)