Sulfaphenazole (Standard), CAS 526-08-9

Product Description: Sulfaphenazole (Standard) is the analytical standard of Sulfaphenazole. This product is intended for research and analytical applications. Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion[1][2][3].

Formula: N/A

References: [1]Qing Chang, et al. Cytochrome P450 2C epoxygenases mediate photochemical stress-induced death of photoreceptors. J Biol Chem. 2014 Mar 21;289(12):8337-52./[2]Shahrzad Elmi, et al. Sulfaphenazole treatment restores endothelium-dependent vasodilation in diabetic mice. Vascul Pharmacol. 2008 Jan;48(1):1-8./[3]Christopher T Turner, et al. Sulfaphenazole reduces thermal and pressure injury severity through rapid restoration of tissue perfusion. Sci Rep. 2022 Jul 23;12(1):12622.

CAS Number: 526-08-9

Molecular Weight: N/A

Research Area: Infection; Cardiovascular Disease

Target: Antibiotic;Apoptosis;Bacterial;Cytochrome P450;Necroptosis

• SKU: MEXHY-B1218R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-B1218R-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK